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Malignant Hyperthermia

Malignant hyperthermia (MH) or malignant hyperpyrexia is a rare life-threatening condition that is triggered by exposure to certain drugs used for general anaesthesia — specifically the volatile anaesthetic agents and suxamethonium, a neuromuscular blocking agent.

General Information


For Patients

If you have been told you or one of your family suffers from Malignant Hyperthermia see our information here.


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For Geneticists

Many MH families appear to have more than one genetic factor contributing to the risk of MH susceptibility.

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For General Practitioners

MH is a rare condition and expert advice is available.

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For Anaesthetists

MH is an acute pharmacogenetic disorder, which develops during or immediately after the application of general anaesthesia.

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Operating Room Staff & anaesthetists

Malignant Hyperthermia
Resource Kit

If you work as an Operating Suite Staff or as an Anaesthetists, MHANZ have developed a Resource Kit for MH.

MH Poster

MH Initial Management

MH Crisis Coordinator

MH Task Cards

View Resource Kit